PPP2CB

Entrez Summary: N/A
UniProt Summary: PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. {ECO:0000269|PubMed:2555176}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

positive regulation of microtubule binding
regulation of microtubule binding
peptidyl-serine dephosphorylation
peptidyl-threonine dephosphorylation
protein phosphatase type 2A complex
response to lead ion
tau protein binding
negative regulation of Ras protein signal transduction
chromosome, centromeric region
negative regulation of small GTPase mediated signal transduction
apoptotic mitochondrial changes
protein serine/threonine phosphatase activity
positive regulation of protein binding
response to hydrogen peroxide
spindle pole
positive regulation of binding
protein C-terminus binding
response to reactive oxygen species
protein dephosphorylation
regulation of protein binding
regulation of Ras protein signal transduction
response to endoplasmic reticulum stress
response to antibiotic
dephosphorylation
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of small GTPase mediated signal transduction
proteasomal protein catabolic process
response to metal ion
regulation of binding
response to oxidative stress
mitochondrion organization
negative regulation of intracellular signal transduction
response to toxic substance
ubiquitin-dependent protein catabolic process
modification-dependent protein catabolic process
response to inorganic substance
modification-dependent macromolecule catabolic process
proteolysis involved in cellular protein catabolic process
cellular protein catabolic process
protein catabolic process