RABL5

Entrez Summary: N/A
UniProt Summary: Small GTPase-like component of the intraflagellar transport (IFT) complex B. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Thapsigargin 0.005μM R07 exp407	-1.81
Bisphenol S 100μM R08 exp458	-1.75
MS094 2μM R03 exp136	1.71
Nicotinamide Riboside 100μM R03 exp139	1.9
Demecolcine 0.03μM R05 exp228	2.02

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

intraciliary transport particle B
intraciliary transport involved in cilium assembly
ciliary tip
intraciliary transport
protein transport along microtubule
microtubule-based protein transport
Rab protein signal transduction
transport along microtubule
cytoskeleton-dependent intracellular transport
microtubule-based transport
cilium
Ras protein signal transduction
protein-containing complex localization
microtubule-based movement
small GTPase mediated signal transduction
GTPase activity
cilium assembly
cilium organization
GTP binding
plasma membrane bounded cell projection assembly
cell projection assembly
centrosome
microtubule-based process
organelle assembly
intracellular protein transport
plasma membrane bounded cell projection organization
cell projection organization
protein transport
intracellular transport
peptide transport
movement of cell or subcellular component
amide transport
cellular protein localization
cellular macromolecule localization
establishment of protein localization
intracellular signal transduction
establishment of localization in cell
nitrogen compound transport