RILPL1

Gene Information
  • Official Symbol: RILPL1
  • Official Name: Rab interacting lysosomal protein like 1
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 353116
  • UniProt: Q5EBL4
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Plays a role in the regulation of cell shape and polarity. Plays a role in cellular protein transport, including protein transport away from primary cilia. Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH (By similarity). Does not regulate lysosomal morphology and distribution. {ECO:0000250}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 2039
  • Expression level (log2 read counts): 3.2

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1