RSL24D1

Entrez Summary: N/A
UniProt Summary: Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of GTPBP4/NOG1 to pre-60S particles (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
RO-3306 3 to 4μM on day4 R04 exp165	-2.02
Dexamethasone 0.006 to 0.015μM on day4 R07 exp352	-1.86
Golgicide-A 4μM R03 exp122	1.77
Sulforaphane 9μM R08 exp526 no dilution day6	1.87

Global Fraction of Cell Lines Where Essential: 739/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	1/1
bile duct	28/28
blood	28/28
bone	26/26
breast	33/33
central nervous system	56/56
cervix	4/4
colorectal	17/17
esophagus	13/13
fibroblast	1/1
gastric	16/16
kidney	21/21
liver	20/20
lung	75/75
lymphocyte	16/16
ovary	26/26
pancreas	24/24
peripheral nervous system	16/16
plasma cell	15/15
prostate	1/1
skin	24/24
soft tissue	9/9
thyroid	2/2
upper aerodigestive	22/22
urinary tract	29/29
uterus	5/5

Expression Distribution

assembly of large subunit precursor of preribosome
ribosomal large subunit assembly
ribosome assembly
cytosolic large ribosomal subunit
ribosomal large subunit biogenesis
structural constituent of ribosome
ribonucleoprotein complex assembly
ribonucleoprotein complex subunit organization
ribosome biogenesis
translation
peptide biosynthetic process
ribonucleoprotein complex biogenesis
amide biosynthetic process
peptide metabolic process
organelle assembly
cellular amide metabolic process
cellular protein-containing complex assembly
nucleolus
RNA binding
organonitrogen compound biosynthetic process
protein-containing complex assembly
cellular nitrogen compound biosynthetic process
cellular macromolecule biosynthetic process
macromolecule biosynthetic process
protein-containing complex subunit organization
gene expression