TMEM11

Entrez Summary: N/A
UniProt Summary: Plays a role in mitochondrial morphogenesis. {ECO:0000269|PubMed:21274005}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Sulforaphane 9μM R08 exp526 no dilution day6	1.76
Demecolcine 0.03μM R05 exp228	1.77
Ribavirin 10 to 15μM on day4 R04 exp160	1.78
WNT3A 44ng/ml R08 exp537	1.83
CFI-400945 25μM R08 exp469	1.84
IL-3 9ng/ml R08 exp493	1.92
BML-284 0.09μM R08 exp460	2.1

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

integral component of mitochondrial inner membrane
inner mitochondrial membrane organization
mitochondrial membrane organization
mitochondrion organization
molecular function
membrane organization
mitochondrion
integral component of plasma membrane