TMX2
Gene Information
- Official Symbol: TMX2
- Official Name: thioredoxin related transmembrane protein 2
- Aliases and Previous Symbols: N/A
- Entrez ID: 51075
- UniProt: Q9Y320
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This protein is enriched on the mitochondria-associated-membrane of the ER via palmitoylation of two of its cytosolically exposed cysteines. [provided by RefSeq, Jan 2017].
- UniProt Summary: N/A
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 755
- Expression level (log2 read counts): 7.04
TMX2 Expression in NALM6 Cells: 7.04
