TMEM161B

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Rotenone 0.07μM R08 exp431	-2.53
Hypoxia 5%O2 R04 exp191	-2.13
QNZ 0.01μM R08 exp439	-2.06
ABT-702 5μM plus CoCl2 18μM R07 exp320	-1.74
Prochlorperazine 5.2μM R02 exp77	1.72
Hydroxyurea 100μM R07 exp329	1.86
Olaparib 4μM R08 exp512	1.97
Dynasore 10μM R04 exp180	1.99
UM0125461 0.74μM R02 exp84	2.01
Genistein 15μM R07 exp360	2.09
Deferoxamine 11μM R07 exp350	2.36
Demecolcine 0.03μM R05 exp228	2.42
Docetaxel 0.002μM R01 exp45	2.53
Vinblastine 0.002μM R01 exp60	2.58
UMK57 1μM R01 exp59	2.67
Mdivi-1 15μM R05 exp217	2.75
Combretastatin A4 0.002 to 0.003μM day4 R04 exp179	3.8
Colchicine 0.009μM R05 exp215	4.41
BML-284 0.09μM R08 exp460	4.54
UM131593 0.2μM R03 exp106	6.03

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

rve
Tmemb 161AB