TRIP10

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Dimethyl-Sulfoxide 1pc R03 exp120	-1.99
IWR1 50μM R08 exp495	-1.74
IU1-C 25μM R04 exp183	-1.7
D-Fructose 10000μM R06 exp279	1.9
Myriocin 25μM R06 exp293	2.17
Rapamycin 2μM plus Cyclosporin-A 3μM R07 exp307	2.59

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

SH3 1
FCH

phagocytic cup
cell projection
cell cortex
lipid binding
lysosome
regulation of small GTPase mediated signal transduction
cytoskeleton
actin cytoskeleton organization
endocytosis
actin filament-based process
import into cell
intracellular membrane-bounded organelle
perinuclear region of cytoplasm
membrane organization
Golgi apparatus
identical protein binding
cytoskeleton organization
regulation of intracellular signal transduction
vesicle-mediated transport