VCX3A
Gene Information
- Official Symbol: VCX3A
- Official Name: variable charge X-linked 3A
- Aliases and Previous Symbols: N/A
- Entrez ID: 51481
- UniProt: Q9NNX9
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. The X-linked members are clustered on chromosome Xp22 and Y-linked members are two identical copies of the gene within a palindromic region on Yq11. The family members share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. The VCX gene cluster is polymorphic in terms of copy number; different individuals may have a different number of VCX genes. VCX/Y genes encode small and highly charged proteins of unknown function. The presence of a putative bipartite nuclear localization signal suggests that VCX/Y members are nuclear proteins. This gene contains 8 repeats of the 30-bp unit. [provided by RefSeq, Jul 2008].
- UniProt Summary: May mediate a process in spermatogenesis or may play a role in sex ratio distortion.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 5339
- Expression level (log2 read counts): -7.68
VCX3A Expression in NALM6 Cells: -7.68
