VPS13D

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 440/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	1/1
bile duct	16/28
blood	11/28
bone	13/26
breast	20/33
central nervous system	36/56
cervix	1/4
colorectal	13/17
esophagus	7/13
fibroblast	0/1
gastric	10/16
kidney	14/21
liver	10/20
lung	47/75
lymphocyte	9/16
ovary	10/26
pancreas	16/24
peripheral nervous system	6/16
plasma cell	9/15
prostate	1/1
skin	17/24
soft tissue	4/9
thyroid	1/2
upper aerodigestive	14/22
urinary tract	15/29
uterus	3/5

Expression Distribution

protein retention in Golgi apparatus
positive regulation of mitophagy
regulation of mitophagy
positive regulation of autophagy of mitochondrion
protein localization to Golgi apparatus
protein targeting to vacuole
regulation of autophagy of mitochondrion
establishment of protein localization to vacuole
protein localization to vacuole
extrinsic component of membrane
positive regulation of macroautophagy
maintenance of protein location in cell
cell
maintenance of location in cell
maintenance of protein location
positive regulation of mitochondrion organization
positive regulation of autophagy
vacuolar transport
maintenance of location
regulation of macroautophagy
regulation of mitochondrion organization
regulation of autophagy
protein targeting
positive regulation of cellular catabolic process
establishment of protein localization to organelle
positive regulation of catabolic process
mitochondrion organization
positive regulation of organelle organization
protein localization to organelle
regulation of cellular catabolic process
regulation of catabolic process
intracellular protein transport
positive regulation of cellular component organization
regulation of organelle organization
protein transport
intracellular transport
peptide transport
amide transport
cellular protein localization
cellular macromolecule localization