ADO

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
GSK-J4 1μM R07 exp362	-2.77
Hydroxychloroquine 30μM R08 exp490	-1.8
THZ531 0.225μM R08 exp444	1.78
LY2090314 0.003μM R08 exp499	1.79
Staurosporine 0.02μM R08 exp524	1.79
Vincristine 0.0005μM R04 exp190	1.8
Selumetinib 20μM R02 exp81	1.85
Hippuristanol 0.12μM R08 exp488	1.86
All-trans-Retinoic-Acid 8μM R07 exp333	1.93
Momordin-Ic 10μM R08 exp506	1.96

Global Fraction of Cell Lines Where Essential: 0/726

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/25
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/15
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/14
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/7
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

cysteamine dioxygenase activity
sulfur amino acid catabolic process
sulfur amino acid metabolic process
sulfur compound catabolic process
cellular amino acid catabolic process
organic acid catabolic process
carboxylic acid catabolic process
cellular amino acid metabolic process
sulfur compound metabolic process
small molecule catabolic process
carboxylic acid metabolic process
oxidation-reduction process
oxoacid metabolic process
organic acid metabolic process
organonitrogen compound catabolic process
small molecule metabolic process
organic substance catabolic process
cellular catabolic process