AGMO

Entrez Summary: N/A
UniProt Summary: Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids. Ether lipids are essential components of brain membranes. {ECO:0000269|PubMed:20643956}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

glyceryl-ether monooxygenase activity
ether lipid metabolic process
glycerol ether metabolic process
ether metabolic process
triglyceride biosynthetic process
neutral lipid biosynthetic process
acylglycerol biosynthetic process
triglyceride metabolic process
acylglycerol metabolic process
neutral lipid metabolic process
iron ion binding
membrane lipid metabolic process
glycerolipid biosynthetic process
glycerolipid metabolic process
lipid biosynthetic process
endoplasmic reticulum membrane
cellular lipid metabolic process
oxidation-reduction process
endoplasmic reticulum
lipid metabolic process
small molecule metabolic process