ATF7IP2

Gene Information
  • Official Symbol: ATF7IP2
  • Official Name: activating transcription factor 7 interacting protein 2
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 80063
  • UniProt: Q5U623
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity (Probable). {ECO:0000305}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 15248
  • Expression level (log2 read counts): 5.4

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1