ATP13A3

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Lenalidomide 20μM R07 exp375	-2.11
Glyphosate 1000μM R06 exp283	-1.96
Hypoxia 5%O2 R04 exp191	-1.88
Tozasertib 0.1μM R07 exp414	-1.8
BRD2 inhibitor II 20μM R07 exp341	-1.76
NMS-873 0.07μM R07 exp380	-1.75
Cyclosporin-A 0.8μM R07 exp347	-1.74
GSK-J5 1.5μM R08 exp484	-1.74
Hippuristanol 0.12μM R08 exp488	1.79
Phenformin 20μM R03 exp143	1.81
Trientine 500μM R08 exp534	1.92
BML-284 0.09μM R08 exp460	1.99
BI-6727 0.001μM R01 exp42	2.05
Suberoylanilide-Hydroxamic-Acid 0.02μM R01 exp53	2.37
SNS-032 25μM R07 exp401	3.28

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

cell
ATPase activity
cellular calcium ion homeostasis
calcium ion homeostasis
cellular divalent inorganic cation homeostasis
divalent inorganic cation homeostasis
cellular metal ion homeostasis
metal ion homeostasis
cellular cation homeostasis
cellular ion homeostasis
cation homeostasis
inorganic ion homeostasis
cellular chemical homeostasis
ion homeostasis
cation transport
cellular homeostasis
chemical homeostasis
ion transport
ATP binding
homeostatic process
membrane