ATP2A3

• Official Symbol: ATP2A3
• Official Name: ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
• Aliases and Previous Symbols: N/A
• Entrez ID: 489
• UniProt: Q93084
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
• UniProt Summary: N/A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 7176
• Expression level (log2 read counts): 9.08

Expression Distribution

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ATP2A3 Expression in NALM6 Cells: 9.08