BEX4
Gene Information
- Official Symbol: BEX4
- Official Name: brain expressed X-linked 4
- Aliases and Previous Symbols: N/A
- Entrez ID: 56271
- UniProt: Q9NWD9
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene is a member of the brain expressed X-linked gene family. The proteins encoded by some of the other members of this family act as transcription elongation factors which allow RNA polymerase II to escape pausing during elongation. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Aug 2011].
- UniProt Summary: May play a role in microtubule deacetylation by negatively regulating the SIRT2 deacetylase activity toward alpha- tubulin and thereby participate to the control of cell cycle progression and genomic stability. {ECO:0000269|PubMed:27512957}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 16974
- Expression level (log2 read counts): -5.6
BEX4 Expression in NALM6 Cells: -5.6
