CAMKV

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Rapamycin 10μM R00 exp30	-2.41
ABT-702 5μM plus Dimethyloxaloylglycine 11μM R07 exp319	-2.11
Radicicol 0.16μM R05 exp242	-1.94
FK-506 30μM R07 exp359	-1.83
BI-2536 0.001μM R01 exp41	-1.8
CCT251545 20μM R07 exp326	1.73
Mitomycin-C 0.06μM R08 exp503	1.79
IL-3 9ng/ml R08 exp493	2.17
Aphidicolin 0.4μM R08 exp440	2.6

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Pkinase Tyr
Pkinase

regulation of modification of postsynaptic structure
regulation of modification of synaptic structure
calmodulin-dependent protein kinase activity
cytoplasmic vesicle membrane
calmodulin binding
regulation of synapse organization
regulation of synapse structure or activity
glutamatergic synapse
protein phosphorylation
phosphorylation
ATP binding