CBY3

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Dexamethasone 0.006 to 0.015μM on day4 R07 exp352	-1.97
Nicotinamide Riboside 100μM R03 exp139	-1.73
Epigallocatechin gallate 20μM R05 exp230	1.7
Clomiphene 4.4μM R02 exp68	1.96

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

ciliary transition zone assembly
ciliary basal body
centriole
negative regulation of Wnt signaling pathway
cilium assembly
regulation of Wnt signaling pathway
cilium organization
plasma membrane bounded cell projection assembly
cell projection assembly
organelle assembly
plasma membrane bounded cell projection organization
cell projection organization
negative regulation of signal transduction
negative regulation of cell communication
negative regulation of signaling
negative regulation of response to stimulus