CCDC86

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Pimelic-diphenylamide-106 5μM R00 exp28	-1.83
THZ531 0.11 to 0.125 to 0.35μM on day4 then day6 R07 exp412	1.88
THZ531 0.11 to 0.125μM on day4 R07 exp410	1.88
Ixabepilone 0.004 to 0.005μM on day4 R04 exp184	1.94
Nifuroxazide 1μM R01 exp51	2.06

Global Fraction of Cell Lines Where Essential: 282/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	1/1
bile duct	13/28
blood	9/28
bone	9/26
breast	9/33
central nervous system	19/56
cervix	2/4
colorectal	9/17
esophagus	4/13
fibroblast	0/1
gastric	6/16
kidney	11/21
liver	9/20
lung	29/75
lymphocyte	5/16
ovary	11/26
pancreas	6/24
peripheral nervous system	7/16
plasma cell	2/15
prostate	0/1
skin	11/24
soft tissue	4/9
thyroid	0/2
upper aerodigestive	10/22
urinary tract	12/29
uterus	1/5

Expression Distribution

Gene	Correlation
PRIM1	0.427
CBWD5	0.402

viral process
symbiotic process
interspecies interaction between organisms
nucleolus
RNA binding