CCNY
Gene Information
- Official Symbol: CCNY
- Official Name: cyclin Y
- Aliases and Previous Symbols: N/A
- Entrez ID: 219771
- UniProt: Q8ND76
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| Cyclin |
| Cyclin N |
GO Terms
| cytoplasmic cyclin-dependent protein kinase holoenzyme complex |
| positive regulation of cyclin-dependent protein serine/threonine kinase activity |
| cyclin-dependent protein serine/threonine kinase regulator activity |
| positive regulation of cyclin-dependent protein kinase activity |
| regulation of cyclin-dependent protein serine/threonine kinase activity |
| regulation of cyclin-dependent protein kinase activity |
| G2/M transition of mitotic cell cycle |
| cell cycle G2/M phase transition |
| mitotic cell cycle phase transition |
| cell cycle phase transition |
| regulation of canonical Wnt signaling pathway |
| positive regulation of protein serine/threonine kinase activity |
| cell-cell signaling by wnt |
| Wnt signaling pathway |
| regulation of Wnt signaling pathway |
| positive regulation of cell cycle |
| cell surface receptor signaling pathway involved in cell-cell signaling |
| protein kinase binding |
| cell division |
| regulation of protein serine/threonine kinase activity |
| positive regulation of protein kinase activity |
| positive regulation of kinase activity |
| mitotic cell cycle process |
| positive regulation of transferase activity |
| mitotic cell cycle |
| regulation of protein kinase activity |
| regulation of kinase activity |
| regulation of transferase activity |
| cell cycle process |
| positive regulation of protein phosphorylation |
| positive regulation of phosphorylation |
| cell-cell signaling |
| positive regulation of phosphorus metabolic process |
| positive regulation of phosphate metabolic process |
| regulation of cell cycle |
| positive regulation of protein modification process |
| cell cycle |
| positive regulation of catalytic activity |
| regulation of protein phosphorylation |
| regulation of phosphorylation |
| positive regulation of cellular protein metabolic process |
| positive regulation of protein metabolic process |
| positive regulation of molecular function |
| regulation of phosphate metabolic process |
| regulation of phosphorus metabolic process |
| regulation of protein modification process |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| 42°C R08 exp539 | -1.73 |
| Nicotinamide Riboside 100μM R03 exp139 | 1.71 |
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 11114
- Expression level (log2 read counts): 5.46
Expression Distribution
CCNY Expression in NALM6 Cells: 5.46