DARS

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 602/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	0/1
bile duct	24/28
blood	26/28
bone	21/26
breast	27/33
central nervous system	49/56
cervix	4/4
colorectal	14/17
esophagus	12/13
fibroblast	1/1
gastric	14/16
kidney	16/21
liver	15/20
lung	66/75
lymphocyte	13/16
ovary	20/26
pancreas	20/24
peripheral nervous system	16/16
plasma cell	14/15
prostate	1/1
skin	17/24
soft tissue	8/9
thyroid	2/2
upper aerodigestive	13/22
urinary tract	22/29
uterus	2/5

Expression Distribution

tRNA anti
tRNA-synt 2

aspartyl-tRNA aminoacylation
aspartate-tRNA ligase activity
aminoacylase activity
aminoacyl-tRNA synthetase multienzyme complex
tRNA aminoacylation for protein translation
tRNA aminoacylation
amino acid activation
tRNA metabolic process
synapse
cellular amino acid metabolic process
translation
peptide biosynthetic process
ncRNA metabolic process
amide biosynthetic process
peptide metabolic process
cellular amide metabolic process
carboxylic acid metabolic process
oxoacid metabolic process
organic acid metabolic process
RNA binding
organonitrogen compound biosynthetic process
ATP binding
protein-containing complex assembly
cellular nitrogen compound biosynthetic process
RNA metabolic process
cellular macromolecule biosynthetic process
small molecule metabolic process
macromolecule biosynthetic process
protein-containing complex subunit organization
membrane
gene expression