DNAJC9

Entrez Summary: N/A
UniProt Summary: May play a role as co-chaperone of the Hsp70 family proteins HSPA1A, HSPA1B and HSPA8. {ECO:0000269|PubMed:17182002}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
UMK57 1μM R01 exp59	-2.51
4-Nitroquinoline-1-oxide 0.5μM R08 exp446	-2.2
ABT-702 5μM plus Deferoxamine 11μM R07 exp321	-2.08
GSK343 3μM R03 exp124	-2.07
AICAR 240μM R05 exp211	-1.95
Ribavirin 10μM R01 exp52	-1.88
Tubastatin-A 2.5μM R07 exp417	-1.88
GSK461364A 0.005μM R03 exp125	-1.72

Global Fraction of Cell Lines Where Essential: 464/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	1/1
bile duct	15/28
blood	21/28
bone	19/26
breast	19/33
central nervous system	39/56
cervix	1/4
colorectal	6/17
esophagus	7/13
fibroblast	1/1
gastric	6/16
kidney	15/21
liver	12/20
lung	46/75
lymphocyte	14/16
ovary	17/26
pancreas	10/24
peripheral nervous system	13/16
plasma cell	14/15
prostate	0/1
skin	13/24
soft tissue	6/9
thyroid	1/2
upper aerodigestive	16/22
urinary tract	18/29
uterus	3/5

Expression Distribution

positive regulation of ATPase activity
heat shock protein binding
regulation of ATPase activity
positive regulation of hydrolase activity
regulation of hydrolase activity
positive regulation of catalytic activity
extracellular space
positive regulation of molecular function