DNTT
Gene Information
- Official Symbol: DNTT
- Official Name: DNA nucleotidylexotransferase
- Aliases and Previous Symbols: N/A
- Entrez ID: 1791
- UniProt: P04053
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells. {ECO:0000250|UniProtKB:P09838}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 17366
- Expression level (log2 read counts): 8.04