DXO

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

RNA pyrophosphohydrolase activity
5-3 exonuclease activity
nuclear mRNA surveillance
nuclear RNA surveillance
RNA surveillance
RNA destabilization
nucleotide binding
mRNA binding
regulation of RNA stability
nuclear-transcribed mRNA catabolic process
magnesium ion binding
mRNA catabolic process
RNA catabolic process
nucleic acid phosphodiester bond hydrolysis
positive regulation of cellular catabolic process
nucleobase-containing compound catabolic process
positive regulation of catabolic process
heterocycle catabolic process
cellular nitrogen compound catabolic process
aromatic compound catabolic process
organic cyclic compound catabolic process
posttranscriptional regulation of gene expression
mRNA metabolic process
regulation of cellular catabolic process
cellular macromolecule catabolic process
regulation of catabolic process
macromolecule catabolic process
RNA metabolic process
negative regulation of gene expression
positive regulation of RNA metabolic process
organic substance catabolic process
cellular catabolic process
positive regulation of nucleobase-containing compound metabolic process