EFTUD2

• Official Symbol: EFTUD2
• Official Name: elongation factor Tu GTP binding domain containing 2
• Aliases and Previous Symbols: N/A
• Entrez ID: 9343
• UniProt: Q15029
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: This gene encodes a GTPase which is a component of the spliceosome complex which processes precursor mRNAs to produce mature mRNAs. Mutations in this gene are associated with mandibulofacial dysostosis with microcephaly. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012].
• UniProt Summary: Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex required for pre-mRNA splicing. Binds GTP.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 311
• Expression level (log2 read counts): 7.85

Expression Distribution

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EFTUD2 Expression in NALM6 Cells: 7.85