ERC1

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

RBD-FIP
Cast

IkappaB kinase complex
leucine zipper domain binding
I-kappaB phosphorylation
I-kappaB kinase/NF-kappaB signaling
presynaptic membrane
PDZ domain binding
retrograde transport, endosome to Golgi
ciliary basal body
cytosolic transport
Rab GTPase binding
positive regulation of NF-kappaB transcription factor activity
endosomal transport
positive regulation of DNA-binding transcription factor activity
synapse
cadherin binding
regulation of DNA-binding transcription factor activity
centrosome
Golgi membrane
negative regulation of apoptotic process
negative regulation of programmed cell death
protein phosphorylation
negative regulation of cell death
phosphorylation
protein transport
intracellular transport
peptide transport
regulation of apoptotic process
regulation of programmed cell death
amide transport
establishment of protein localization
regulation of cell death
intracellular signal transduction
positive regulation of molecular function
establishment of localization in cell
nitrogen compound transport
vesicle-mediated transport