FUT7

Entrez Summary: The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of sialyl-Lewis X antigens. The encoded protein can direct the synthesis of the E-selectin-binding sialyl-Lewis X moiety. [provided by RefSeq, Jul 2008].
UniProt Summary: Catalyzes alpha-1,3 glycosidic linkages involved in the expression of sialyl Lewis X antigens. {ECO:0000269|PubMed:11404359, ECO:0000269|PubMed:8207002, ECO:0000269|PubMed:9299472}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

leukocyte migration involved in immune response
CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
regulatory T cell differentiation
alpha-(1→3)-fucosyltransferase activity
fucosyltransferase activity
L-fucose catabolic process
fucose catabolic process
L-fucose metabolic process
fucose metabolic process
fucosylation
CD4-positive, alpha-beta T cell differentiation
CD4-positive, alpha-beta T cell activation
alpha-beta T cell differentiation
hexose catabolic process
alpha-beta T cell activation
monosaccharide catabolic process
ceramide metabolic process
Golgi cisterna membrane
carbohydrate catabolic process
T cell differentiation
sphingolipid metabolic process
hexose metabolic process
monosaccharide metabolic process
membrane lipid metabolic process
T cell activation
lymphocyte differentiation
macromolecule glycosylation
protein glycosylation
glycosylation
glycoprotein biosynthetic process
leukocyte differentiation
leukocyte migration
lymphocyte activation
glycoprotein metabolic process
small molecule catabolic process
carbohydrate metabolic process
hemopoiesis
hematopoietic or lymphoid organ development
carbohydrate derivative biosynthetic process
immune system development