GABRQ
Gene Information
- Official Symbol: GABRQ
- Official Name: gamma-aminobutyric acid type A receptor subunit theta
- Aliases and Previous Symbols: N/A
- Entrez ID: 55879
- UniProt: Q9UN88
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes the theta subunit of the GABA A receptor. The gene is mapped to chromosome Xq28 in a cluster of genes including those that encode the alpha 3 and epsilon subunits of the GABA A receptor. [provided by RefSeq, Jul 2017].
- UniProt Summary: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 14196
- Expression level (log2 read counts): -5.6