GAPVD1

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Cycloheximide 0.02μM R00 exp14	-1.92
Rotenone 20μM R00 exp34	-1.83
DABN 2μM R00 exp16	-1.82
ABT-702 5μM plus Deferoxamine 11μM R07 exp321	-1.76
Rifampicin 10μM R00 exp32	-1.74
Zebularine 20μM R07 exp423	1.83

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

VPS9
RasGAP

GTPase activating protein binding
guanyl-nucleotide exchange factor activity
endosome
GTPase activator activity
cadherin binding
positive regulation of GTPase activity
regulation of GTPase activity
endocytosis
import into cell
regulation of protein transport
regulation of peptide transport
regulation of establishment of protein localization
positive regulation of hydrolase activity
membrane organization
regulation of protein localization
regulation of hydrolase activity
positive regulation of catalytic activity
positive regulation of molecular function
regulation of transport
vesicle-mediated transport
membrane