GJC3
Gene Information
- Official Symbol: GJC3
- Official Name: gap junction protein gamma 3
- Aliases and Previous Symbols: N/A
- Entrez ID: 349149
- UniProt: Q8NFK1
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a gap junction protein. The encoded protein, also known as a connexin, plays a role in formation of gap junctions, which provide direct connections between neighboring cells. Mutations in this gene have been reported to be associated with nonsyndromic hearing loss.[provided by RefSeq, Feb 2010].
- UniProt Summary: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. {ECO:0000250}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 2274
- Expression level (log2 read counts): -2.64