GJC3

Gene Information
  • Official Symbol: GJC3
  • Official Name: gap junction protein gamma 3
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 349149
  • UniProt: Q8NFK1
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: This gene encodes a gap junction protein. The encoded protein, also known as a connexin, plays a role in formation of gap junctions, which provide direct connections between neighboring cells. Mutations in this gene have been reported to be associated with nonsyndromic hearing loss.[provided by RefSeq, Feb 2010].
  • UniProt Summary: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. {ECO:0000250}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 2274
  • Expression level (log2 read counts): -2.64

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1