HINT2

Entrez Summary: N/A
UniProt Summary: Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity. {ECO:0000269|PubMed:16762638, ECO:0000269|PubMed:18653718}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

HIT
DcpS C

negative regulation of peptidyl-lysine acetylation
negative regulation of protein acetylation
nucleotide binding
regulation of peptidyl-lysine acetylation
regulation of protein acetylation
hydrolase activity
steroid biosynthetic process
steroid metabolic process
lipid catabolic process
lipid biosynthetic process
negative regulation of protein modification process
nucleolus
apoptotic process
negative regulation of cellular protein metabolic process
programmed cell death
cell death
negative regulation of protein metabolic process
lipid metabolic process
mitochondrion
organic cyclic compound biosynthetic process
organic substance catabolic process
regulation of protein modification process