HNRNPH3

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Fas-L 44ng/ml R08 exp482	-1.88
BRD2 inhibitor II 20μM R07 exp341	-1.87
LY2090314 0.003μM R08 exp500 no dilution day6	-1.87
MS023 7μM R03 exp135	-1.79
Dexamethasone 0.006μM R07 exp351	-1.78
Adefovir 20μM R07 exp332	-1.77
Docosahexaenoic-acid 50μM R07 exp356	-1.72
UM0125461 0.74μM R02 exp84	1.84
DKK1 89ng/ml R08 exp477	1.91
LLY-284 2.6μM R06 exp291	2.42

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

spliceosomal complex
mRNA splicing, via spliceosome
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
RNA splicing, via transesterification reactions
RNA splicing
mRNA processing
epithelial cell differentiation
mRNA metabolic process
RNA processing
epithelium development
RNA binding
RNA metabolic process
tissue development
gene expression