MARCO

Gene Information
  • Official Symbol: MARCO
  • Official Name: macrophage receptor with collagenous structure
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 8685
  • UniProt: Q9UEW3
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Pattern recognition receptor (PRR) which binds Gram- positive and Gram-negative bacteria (PubMed:9468508). Also plays a role in binding of unopsonized particles by alveolar macrophages (By similarity). Binds to the secretoglobin SCGB3A2 (PubMed:12847263). {ECO:0000250|UniProtKB:Q9WUB9, ECO:0000269|PubMed:12847263, ECO:0000269|PubMed:9468508}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 9063
  • Expression level (log2 read counts): -7.68

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1