METTL21C

Entrez Summary: N/A
UniProt Summary: Protein-lysine methyltransferase. {ECO:0000269|PubMed:22948820}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

hormone-mediated apoptotic signaling pathway
protein-lysine N-methyltransferase activity
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
cellular response to dexamethasone stimulus
response to dexamethasone
cellular response to glucocorticoid stimulus
heat shock protein binding
cellular response to corticosteroid stimulus
regulation of release of sequestered calcium ion into cytosol
peptidyl-lysine methylation
cellular response to ketone
response to antineoplastic agent
regulation of calcium ion transport into cytosol
skeletal muscle tissue development
regulation of sequestering of calcium ion
skeletal muscle organ development
protein alkylation
protein methylation
response to glucocorticoid
regulation of calcium ion transmembrane transport
response to corticosteroid
hormone-mediated signaling pathway
cellular response to xenobiotic stimulus
cellular response to steroid hormone stimulus
response to ketone
regulation of calcium ion transport
macromolecule methylation
apoptotic signaling pathway
striated muscle tissue development
muscle organ development
muscle tissue development
response to xenobiotic stimulus
methylation
peptidyl-lysine modification
response to steroid hormone
regulation of cation transmembrane transport
regulation of metal ion transport
cellular response to drug
muscle structure development
regulation of ion transmembrane transport