MTRNR2L3

Entrez Summary: N/A
UniProt Summary: Plays a role as a neuroprotective and antiapoptotic factor. {ECO:0000250|UniProtKB:Q8IVG9}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
GSK-J4 1.5μM R08 exp441	-2.22
Nocodazole 0.02μM R00 exp23	-2.09
TIC10 10μM R08 exp532	-1.73
Radicicol 0.16μM R05 exp242	1.7
BI-2536 0.0042μM R03 exp95	1.75
Glyphosate 1000μM R06 exp283	1.75
Pterostilbene 16μM R02 exp78	1.75
Cadmium 60μM R08 exp462	1.77
Taxol 0.002μM R01 exp54	1.82
4-Nitroquinoline-1-oxide 0.5μM R08 exp446	1.92

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

negative regulation of execution phase of apoptosis
receptor antagonist activity
regulation of execution phase of apoptosis
negative regulation of signaling receptor activity
regulation of signaling receptor activity
negative regulation of apoptotic process
negative regulation of programmed cell death
negative regulation of cell death
negative regulation of molecular function
regulation of apoptotic process
regulation of programmed cell death
regulation of cell death
extracellular region