NCAPD2
Gene Information
- Official Symbol: NCAPD2
- Official Name: non-SMC condensin I complex subunit D2
- Aliases and Previous Symbols: N/A
- Entrez ID: 9918
- UniProt: Q15021
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. May target the condensin complex to DNA via its C-terminal domain. {ECO:0000269|PubMed:11136719}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 708
- Expression level (log2 read counts): 8.76