NTSR2

Entrez Summary: N/A
UniProt Summary: Receptor for the tridecapeptide neurotensin. It is associated with G proteins that activate a phosphatidylinositol- calcium second messenger system.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Beta-Estradiol 0.55μM R07 exp425	-1.99
Pyridostatin 4μM R05 exp240	-1.75
Dimethyloxaloylglycine 100μM R05 exp229	-1.74
Deguelin 0.05μM R02 exp69	-1.73

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

G protein-coupled neurotensin receptor activity
phospholipase C-activating G protein-coupled receptor signaling pathway
neuropeptide signaling pathway
regulation of membrane potential
G protein-coupled receptor activity
sensory perception
G protein-coupled receptor signaling pathway
nervous system process
integral component of plasma membrane
system process