PCDH1

Entrez Summary: N/A
UniProt Summary: May be involved in cell-cell interaction processes and in cell adhesion.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Olaparib 4μM R08 exp512	-1.74
2-Methoxyestradiol 0.2μM R01 exp40	1.89
2-Methoxyestradiol 0.55 to 0.75μM on day4 R07 exp311	1.97
BI-6727 0.001μM R01 exp42	2.02
YM155 0.0002μM R01 exp61	2.27

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Cadherin
Protocadherin

homophilic cell adhesion via plasma membrane adhesion molecules
cell-cell junction
cell-cell adhesion via plasma-membrane adhesion molecules
cell-cell adhesion
cell junction
intracellular membrane-bounded organelle
calcium ion binding
nucleolus
cell adhesion
biological adhesion
cell-cell signaling
integral component of plasma membrane