PEX10
Gene Information
- Official Symbol: PEX10
- Official Name: peroxisomal biogenesis factor 10
- Aliases and Previous Symbols: N/A
- Entrez ID: 5192
- UniProt: O60683
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a protein involved in import of peroxisomal matrix proteins. This protein localizes to the peroxisomal membrane. Mutations in this gene result in phenotypes within the Zellweger spectrum of peroxisomal biogenesis disorders, ranging from neonatal adrenoleukodystrophy to Zellweger syndrome. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
- UniProt Summary: Somewhat implicated in the biogenesis of peroxisomes.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 1992
- Expression level (log2 read counts): 3.93