PKDREJ

Entrez Summary: N/A
UniProt Summary: May have a central role in fertilization. May generate a Ca(2+) transporting channel directly involved in initiating the acrosome reaction of the sperm.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

acrosome reaction
detection of mechanical stimulus
calcium channel activity
detection of external stimulus
detection of abiotic stimulus
single fertilization
fertilization
calcium ion transmembrane transport
response to mechanical stimulus
calcium ion transport
divalent metal ion transport
divalent inorganic cation transport
inorganic cation transmembrane transport
cation transmembrane transport
metal ion transport
inorganic ion transmembrane transport
detection of stimulus
calcium ion binding
cation transport
sexual reproduction
ion transmembrane transport
multi-organism reproductive process
response to abiotic stimulus
transmembrane transport
ion transport
reproductive process
reproduction
membrane