PNN

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 96/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	1/1
bile duct	4/28
blood	7/28
bone	5/26
breast	4/33
central nervous system	8/56
cervix	0/4
colorectal	1/17
esophagus	1/13
fibroblast	0/1
gastric	1/16
kidney	4/21
liver	4/20
lung	5/75
lymphocyte	2/16
ovary	2/26
pancreas	1/24
peripheral nervous system	2/16
plasma cell	4/15
prostate	0/1
skin	5/24
soft tissue	1/9
thyroid	0/2
upper aerodigestive	1/22
urinary tract	2/29
uterus	1/5

Expression Distribution

Pinin SDK memA
Pinin SDK N

exon-exon junction complex
desmosome
catalytic step 2 spliceosome
intermediate filament
cell-cell junction
structural molecule activity
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
mRNA splicing, via spliceosome
RNA splicing, via transesterification reactions
RNA splicing
nuclear speck
mRNA processing
mRNA metabolic process
RNA processing
cell adhesion
biological adhesion
RNA binding
DNA binding
RNA metabolic process
membrane
gene expression