PTMS

Entrez Summary: N/A
UniProt Summary: Parathymosin may mediate immune function by blocking the effect of prothymosin alpha which confers resistance to certain opportunistic infections.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
HMS-I2 10μM R06 exp288	-2.73
Rapamycin 2μM plus Cyclosporin-A 3μM R07 exp307	-2.7
ABT-702 5μM plus Dimethyloxaloylglycine 11μM R07 exp319	-2.62
JQ1 0.01μM R03 exp130	-2.15
Sucrose 20000μM R06 exp298	-1.93
GSK343 3μM R03 exp124	-1.88
THZ531 0.225μM R08 exp444	-1.85
THZ531 0.11 to 0.125 to 0.35μM on day4 then day6 R07 exp412	-1.84
Phenformin 20μM R05 exp212	-1.79
PU-H71 1μM R08 exp515	1.76
Mubritinib 0.2μM R01 exp48	1.85
Rapamycin 10μM R00 exp30	1.94
Tanespimycin 14μM R08 exp527	2.09

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

DNA replication
cellular macromolecule biosynthetic process
macromolecule biosynthetic process