RBM28
Gene Information
- Official Symbol: RBM28
- Official Name: RNA binding motif protein 28
- Aliases and Previous Symbols: N/A
- Entrez ID: 55131
- UniProt: Q9NW13
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The protein encoded by this gene is a specific nucleolar component of the spliceosomal small nuclear ribonucleoprotein (snRNP)complexes . It specifically associates with U1, U2, U4, U5, and U6 small nuclear RNAs (snRNAs), possibly coordinating their transition through the nucleolus. Mutation in this gene causes alopecia, progressive neurological defects, and endocrinopathy (ANE syndrome), a pleiotropic and clinically heterogeneous disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].
- UniProt Summary: Nucleolar component of the spliceosomal ribonucleoprotein complexes. {ECO:0000269|PubMed:17081119}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 1274
- Expression level (log2 read counts): 7.18
RBM28 Expression in NALM6 Cells: 7.18
