RBMS3

Entrez Summary: N/A
UniProt Summary: Binds poly(A) and poly(U) oligoribonucleotides. {ECO:0000269|PubMed:10675610}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
2-Methoxyestradiol 0.55 to 0.75μM on day4 R07 exp311	1.7
HMS-I1 1μM R01 exp46	1.77
ABT-702 5μM plus Dimethyloxaloylglycine 11μM R07 exp319	1.78
Azithromycin 100μM R08 exp452	1.93
NFN1 0.1μM R01 exp49	1.94
Lapatinib 5μM R01 exp47	2.12
Selumetinib 20μM R02 exp81	2.28

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

defense response to tumor cell
response to tumor cell
poly(A) binding
mRNA 3-UTR AU-rich region binding
poly(U) RNA binding
mRNA 3-UTR binding
positive regulation of translation
positive regulation of cellular amide metabolic process
ribonucleoprotein complex
negative regulation of canonical Wnt signaling pathway
negative regulation of Wnt signaling pathway
regulation of canonical Wnt signaling pathway
regulation of translation
regulation of Wnt signaling pathway
regulation of cellular amide metabolic process
posttranscriptional regulation of gene expression
negative regulation of signal transduction
response to biotic stimulus
defense response
negative regulation of cell communication
negative regulation of signaling
RNA binding
positive regulation of cellular protein metabolic process
negative regulation of response to stimulus
positive regulation of protein metabolic process
negative regulation of gene expression
positive regulation of macromolecule biosynthetic process
positive regulation of cellular biosynthetic process
positive regulation of gene expression
positive regulation of biosynthetic process