S100A7
Gene Information
- Official Symbol: S100A7
- Official Name: S100 calcium binding protein A7
- Aliases and Previous Symbols: N/A
- Entrez ID: 6278
- UniProt: P31151
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| S 100 |
GO Terms
| RAGE receptor binding |
| sequestering of metal ion |
| positive regulation of T cell chemotaxis |
| regulation of T cell chemotaxis |
| positive regulation of monocyte chemotaxis |
| positive regulation of lymphocyte chemotaxis |
| positive regulation of mononuclear cell migration |
| regulation of monocyte chemotaxis |
| positive regulation of granulocyte chemotaxis |
| regulation of lymphocyte chemotaxis |
| positive regulation of T cell migration |
| positive regulation of lymphocyte migration |
| regulation of granulocyte chemotaxis |
| regulation of T cell migration |
| regulation of mononuclear cell migration |
| regulation of lymphocyte migration |
| antimicrobial humoral immune response mediated by antimicrobial peptide |
| defense response to Gram-negative bacterium |
| positive regulation of leukocyte chemotaxis |
| azurophil granule lumen |
| antimicrobial humoral response |
| regulation of leukocyte chemotaxis |
| positive regulation of leukocyte migration |
| positive regulation of chemotaxis |
| maintenance of location |
| response to reactive oxygen species |
| regulation of leukocyte migration |
| positive regulation of ERK1 and ERK2 cascade |
| regulation of chemotaxis |
| keratinocyte differentiation |
| regulation of ERK1 and ERK2 cascade |
| response to lipopolysaccharide |
| epidermal cell differentiation |
| angiogenesis |
| response to molecule of bacterial origin |
| defense response to bacterium |
| humoral immune response |
| collagen-containing extracellular matrix |
| skin development |
| response to oxidative stress |
| blood vessel morphogenesis |
| epidermis development |
| focal adhesion |
| neutrophil degranulation |
| blood vessel development |
| neutrophil activation involved in immune response |
| neutrophil mediated immunity |
| positive regulation of cell migration |
| neutrophil activation |
| granulocyte activation |
| leukocyte degranulation |
| vasculature development |
| myeloid leukocyte mediated immunity |
| cardiovascular system development |
| positive regulation of cell motility |
| myeloid cell activation involved in immune response |
| positive regulation of cellular component movement |
| positive regulation of MAPK cascade |
| positive regulation of locomotion |
| myeloid leukocyte activation |
| positive regulation of response to external stimulus |
| leukocyte activation involved in immune response |
| cell activation involved in immune response |
| tube morphogenesis |
| epithelial cell differentiation |
| response to bacterium |
| regulated exocytosis |
| calcium ion binding |
| regulation of MAPK cascade |
| innate immune response |
| leukocyte mediated immunity |
| exocytosis |
| zinc ion binding |
| tube development |
| regulation of cell migration |
| response to lipid |
| circulatory system development |
| anatomical structure formation involved in morphogenesis |
| regulation of cell motility |
| leukocyte activation |
| defense response to other organism |
| regulation of locomotion |
| regulation of cellular component movement |
| secretion by cell |
| endoplasmic reticulum |
| positive regulation of protein phosphorylation |
| positive regulation of intracellular signal transduction |
| export from cell |
| positive regulation of phosphorylation |
| cell activation |
| immune effector process |
| regulation of response to external stimulus |
| epithelium development |
| secretion |
| positive regulation of phosphorus metabolic process |
| positive regulation of phosphate metabolic process |
| positive regulation of immune system process |
| positive regulation of protein modification process |
| response to other organism |
| response to external biotic stimulus |
| response to biotic stimulus |
| defense response |
| regulation of protein phosphorylation |
| response to oxygen-containing compound |
| regulation of phosphorylation |
| extracellular space |
| positive regulation of cellular protein metabolic process |
| positive regulation of signal transduction |
| regulation of immune system process |
| positive regulation of protein metabolic process |
| tissue development |
| regulation of phosphate metabolic process |
| regulation of phosphorus metabolic process |
| positive regulation of cell communication |
| positive regulation of signaling |
| regulation of intracellular signal transduction |
| regulation of protein modification process |
| immune response |
| extracellular region |
| vesicle-mediated transport |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
| Gene | Correlation |
|---|---|
| RRM1 | 0.476 |
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 17732
- Expression level (log2 read counts): -7.68
Expression Distribution
S100A7 Expression in NALM6 Cells: -7.68
