SFXN3

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
RS-1 10μM R08 exp519	-1.93
Dynasore 7μM R08 exp436	1.84

serine transmembrane transporter activity
serine import into mitochondrion
serine transport
amino acid import
one-carbon metabolic process
neutral amino acid transport
amino acid transmembrane transport
mitochondrial transmembrane transport
mitochondrial membrane
amino acid transport
organic acid transmembrane transport
carboxylic acid transmembrane transport
mitochondrial transport
anion transmembrane transport
carboxylic acid transport
organic acid transport
organic anion transport
anion transport
cation transmembrane transport
cation transport
ion transmembrane transport
mitochondrion
transmembrane transport
ion transport
small molecule metabolic process
nitrogen compound transport