SH3BGRL2

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Ethanol 0.01 R05 exp234	-1.86
All-trans-Retinoic-Acid 40μM R07 exp334	1.7
Betulinic acid 10 to 15μM on day4 R05 exp222	1.7
LB-100 2μM R05 exp210	1.7
Etoposide 0.1μM R05 exp198	1.71
All-trans-Retinoic-Acid 8μM R07 exp333	1.79
Deferoxamine 11μM R07 exp350	1.88
ABT-702 5μM plus CoCl2 18μM R07 exp320	1.96

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

SH3BGR
Glutaredoxin

SH3 domain binding
nuclear membrane