SLC19A2
Gene Information
- Official Symbol: SLC19A2
- Official Name: solute carrier family 19 member 2
- Aliases and Previous Symbols: N/A
- Entrez ID: 10560
- UniProt: O60779
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes the thiamin transporter protein. Mutations in this gene cause thiamin-responsive megaloblastic anemia syndrome (TRMA), which is an autosomal recessive disorder characterized by diabetes mellitus, megaloblastic anemia and sensorineural deafness. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016].
- UniProt Summary: High-affinity transporter for the intake of thiamine. {ECO:0000269|PubMed:10391222, ECO:0000269|PubMed:10542220}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 16500
- Expression level (log2 read counts): -6.6