SLC27A3

Gene Information
  • Official Symbol: SLC27A3
  • Official Name: solute carrier family 27 member 3
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 11000
  • UniProt: Q5K4L6
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: This gene belongs to a family of integral membrane proteins and encodes a protein that is involved in lipid metabolism. The increased expression of this gene in human neural stem cells derived from induced pluripotent stem cells suggests that it plays an important role in early brain development. Naturally occurring mutations in this gene are associated with autism spectrum disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017].
  • UniProt Summary: Has acyl-CoA ligase activity for long-chain and very- long-chain fatty acids. Does not exhibit fatty acid transport activity (By similarity). {ECO:0000250}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 12180
  • Expression level (log2 read counts): 4.02

Expression Distribution

  • Last modified: 2026/01/07 22:37
  • by 127.0.0.1