SLC31A1

Entrez Summary: N/A
UniProt Summary: High-affinity, saturable copper transporter involved in dietary copper uptake. {ECO:0000269|PubMed:11734551}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

copper ion import across plasma membrane
plasma membrane copper ion transport
copper ion transmembrane transporter activity
cellular response to cisplatin
copper ion transmembrane transport
copper ion import
response to cisplatin
cellular copper ion homeostasis
copper ion transport
copper ion homeostasis
drug transmembrane transport
inorganic ion import across plasma membrane
inorganic cation import across plasma membrane
response to antineoplastic agent
import across plasma membrane
cellular transition metal ion homeostasis
recycling endosome
transition metal ion transport
late endosome
transition metal ion homeostasis
drug transport
cellular response to toxic substance
neuronal cell body
cellular response to drug
response to toxic substance
cellular metal ion homeostasis
inorganic cation transmembrane transport
cation transmembrane transport
metal ion homeostasis
cellular cation homeostasis
metal ion transport
cellular ion homeostasis
inorganic ion transmembrane transport
import into cell
cation homeostasis
inorganic ion homeostasis
cellular chemical homeostasis
ion homeostasis
cation transport
cellular homeostasis